Binding of 125I-insulin to the isolated glomeruli of rat kidney.

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Binding of 125I-insulin to the isolated glomeruli of rat kidney.

To investigate a possible action of insulin on the glomerulus, the binding 125I-insulin to the isolated glomeruli prepared from rat kidney was examined. When incubated at 22 degrees C, 125I-insulin binding proceeded with time and reached a steady state at 45 min at which time nonspecific binding was less than 25% of total binding. A small fraction of 125I-insulin was degraded during incubation....

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1979

ISSN: 0021-9738

DOI: 10.1172/jci109592